Formulation Strategies For Improved Dermal & Oral Drug Delivery
3 March 2023
Prof. Cornelia M. Keck
Cornelia M. Keck is a pharmacist and obtained her PhD in 2006 from the Freie Universität (FU) in Berlin. In 2009 she was appointed as Adjunct Professor for Pharmaceutical and Nutritional Nanotechnology at the University Putra Malaysia (UPM) and in 2011 she obtained her Venia legendi (Habilitation) at the Freie Universität Berlin and was appointed as a Professor for Pharmacology and Pharmaceutics at the University of Applied Sciences Kaiserslautern. Since 2016 she is Professor of Pharmaceutics and Biopharmaceutics at the Philipps-Universität Marburg.
Her field of research is the development and characterization of innovative nanocarriers for improved delivery of poorly soluble actives for healthcare and cosmetics. Prof. Keck is executive board member of the German Association of Nanotechnology (Deutscher Verband Nanotechnologie), Vize-chairman of the unit „Dermocosmetics“ at the German Society of Dermopharmacy, active member in many pharmaceutical societies and member of the BfR Committee for Cosmetics at the Federal Institute for Risk Assessment (BfR).
Active pharmaceutical compounds (API) can only be taken up by the body if a sufficient amount of the API is available in dissolved state at the site of absorption. However, today, most of the newly developed small molecules that come from chemical synthesis possess extremely poor aqueous solubility and thus cannot be taken up by the body sufficiently. Therefore, innovative formulation principles that increase the solubility of such API are of high importance. The talk will provide an overview of novel formulation strategies that can help to overcome poor solubility. Special focus will be on simple but smart formulation strategies for oral and dermal drug delivery.